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Senior Scientist Up Stream Processing (USP) COVID-19

Are you an experienced Scientist in the field of USP processes and looking for a next step in your career? Interested in working on COVID-19 vaccine? This may be the position for you! #corona

Job Description

You will work within the USP department which is responsible for early- as well as late-stage development of scalable, pharmaceutical-grade production processes for viral vaccines using mammalian cell lines as a production platform. Novel technologies are used to make sure that the processes are safe, reliable, scalable and cost-effective, so that the vaccines can be produced in large quantities at low costs. The developed production processes are transferred into GMP production facilities to produce clinical batches and scaled-up for commercial production. This is done in close collaboration with many partners in Discovery, Development and Supply Chain in an international environment. Within the USP department, a lab team is responsible for performing all hands-on experimental activities, data processing and documentation, whereas a team of scientists is responsible for the overall scientific approach and progress within our projects. Currently the department is ofucssing on advances in COVID-19 vaccine


  • Leads teams of motivated process developers

  • Develops and executes USP early- and late-stage development and tech transfer strategies

  • Creates and manages research plans with greater complexity in the delivery of business results

  • Represents USP in multidisciplinary project team(s)

  • Acts as senior author in the preparation of presentations, technical reports, documents for regulatory filing and patents

  • Applies the latest technological innovations into the daily work. One of the major innovations currently explored is modeling, data management and statistical analysis applied to bioprocessing


  • Ph. D. degree or post-doctorate degree biopharmaceutical sciences, biotechnology, engineering or related fields

  • * At least 6 years of late-stage biopharmaceutical experience (of which at least some years in industry)

  • * Technical knowledge on bioreactor process technology; ideally for R&D and/or commercial (GMP) purposes

  • * Experience with two or more of the following: life cycle process validation; regulatory submission writing; process improvements; technology transfer; manufacturing support

  • We're looking for someone with coaching and leadership capabilities. Someone of high integrity & instilling trust, and able to help the team make decisions and formulate priorities.


  • Employment: Initially via Oxford global Resources, with prospect of a permanent contract

  • Salary indication: from € 4700 to € 6000

  • Working hours: 40 hours per week (part-time can be discussed)

  • Holidays: 25 (+12)

  • Location: Leiden region

Vacancy number; 15110